154592-95-7Relevant academic research and scientific papers
Construction of Tetracyclic Indole Bases via Aza Diels-Alder Reaction of Indolylethylimines with Brassard's Diene
Lock, Ralf,Waldmann, Herbert
, p. 511 - 516 (2007/10/02)
Schiff's bases 3 derived from tryptamine react with Brassard's diene 4 in the presence of EtAlCl2 to give functionalized 1,2 5,6-tetrahydropyridines which are subsequently transformed to indoloquinolizines 8-10 by the Bischler-Napieralski reaction and reduction of the intermediate iminium salts with NaBH4. - Key Words: Diels-Alder reactions / Bischler-Napieralski reactions / Brassard's diene / Indoloquinolizines / Alkaloids
