154606-56-1

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 60702-69-4 2-chloro-4-fluorobenzonitrile 

Downstream Products

• 1189140-45-1 2-chloro-4-(4-formyl-3,5-dimethyl-1H-pyrazol-1-yl)-benzonitrile 
• 1189140-48-4 [1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl](oxo)acetyl chloride 
• 1189140-49-5 1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazole-4-carbonyl chloride 
• 1189140-57-5 4-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-chlorobenzonitrile 
• 1189140-58-6 2-chloro-4-(4-iodo-3,5-dimethyl-1H-pyrazol-1-yl)benzonitrile 
• 1189140-56-4 N-[4-(aminocarbonyl)benzyl]-1-[4-(aminocarbonyl)-3-chlorophenyl]-3,5-dimethyl-1H-pyrazole-4-carboxamide 
• 1189134-85-7 2-chloro-4-(4-{3-[(4-fluorophenyl)sulfonyl]-2-oxopropanoyl}-3,5-dimethyl-1H-pyrazol-1-yl)benzonitrile 
• 1189134-93-7 2-[1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-N-(4-fluorobenzyl)-2-oxoacetamide 
• 1189135-35-0 4-[({[1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]carbonyl}amino)methyl]benzoic acid 
• 1189135-55-4 N-(4-carbamoylbenzyl)-1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxamide 
• 1189135-04-3 methyl 4-[({[1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]carbonyl}amino)methyl]benzoate 
• 1189135-48-5 1-(3-chloro-4-cyanophenyl)-N-[(6-cyanopyridin-3-yl)methyl]-3,5-dimethyl-1H-pyrazole-4-carboxamide 
• 1189135-03-2 4-{[1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]methoxy}benzamide 
• 1189134-92-6 1-(3-chloro-4-cyanophenyl)-N-(4-fluorobenzyl)-3,5-dimethyl-1H-pyrazole-4-carboxamide 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of 4-arylmethyl-1- phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists

A series of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole compounds B were designed, synthesized, and evaluated for their potential as new-generation androgen receptor (AR) antagonists therapeutically effective against castration-resistant

SUBSTITUTED PYRAZOLE DERIVATIVES AND USE THEREOF

The present invention aims to provide a pyrazole derivative represented by the formula (I') or a salt thereof.