1546765-39-2Relevant academic research and scientific papers
Sustainable and Cost-Effective Suzuki-Miyaura Couplings toward the Key Biaryl Subunits of Arylex and Rinskor Active
Irvine, Nicholas M.,Li, Xiaoyong,Lipshutz, Bruce H.,Schuitman, Abraham D.,Takale, Balaram S.,Thakore, Ruchita R.
, (2020/07/03)
Challenging Suzuki-Miyaura cross couplings associated with novel crop protection active ingredients from Corteva Agriscience, Arylex and Rinskor, can be performed in water using parts per million (ppm) levels of a Pd catalyst. Each coupling required a distinct set of reaction conditions to achieve maximum selectivities and chemical yields. By way of comparison, this chemistry is not only performed under environmentally responsible aqueous micellar conditions, but also involves lowering loadings (3-5 times) of endangered palladium than used previously to attain a more sustainable process.
RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING
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Paragraph 0064, (2016/12/12)
Methods for the recovery and/or reuse of palladium catalyst after a Suzuki coupling reaction in which two molecules are coupled are described.
