1547-51-9Relevant academic research and scientific papers
Room-temperature Reactions of CsSO4F with Organic Molecules containing Heteroatoms
Stavber, Stojan,Zupan, Marko
, p. 563 - 564 (1983)
Room-temperature fluorination of pentane-2,4-dione with CsSO4F gave 3-fluoro and 1,3-difluoro derivatives, while 5,5-difluorobarbituric acid was formed in high yield in a 2 h reaction at 100 deg C; 1,3-dimethyluracil was converted in methanol via cis- and trans-5-fluoro-6-methoxy derivatives into 5-fluoro-1,3-dimethyluracil in high yield and uridine into 5-fluorouridine.
Direct fluorination of 1,3-dicarbonyl compounds
Chambers, Richard D.,Greenhall, Martin P.,Hutchinson, John
, p. 1 - 8 (2007/10/02)
In acid media, 1,3-diketones and 1,3-keloesters can be fluorinated in high yield and often with high conversion mainly to the corresponding 2-fluoro- compounds. Diesters such as diethyl malonate do not react with fluorine under the same reaction conditions. The mechanism of these reactions has been investigated and while the identity of the electrophilic fluorinating species is uncertain, we believe that the essential features of the reaction pathway are understood. Copyright
Direct Fluorination of 1,3-Dicarbonyl Compounds
Chambers, Richard D.,Greenhall, Martin P.,Hutchinson, John
, p. 21 - 22 (2007/10/02)
1,3-Dicarbonyls, such as 1,3-diketones and 1,3-ketoesters, react directly with elemental fluorine at room temperature to give the corresponding 2-fluoro- and, in some cases, 2,2-difluoro-compounds in high yield.
