1547221-53-3Relevant academic research and scientific papers
DDQ-mediated oxidative coupling: An approach to 2,3-dicyanofuran (thiophene)
Wang, Zheng-Lin,Li, Hong-Liang,Ge, Li-Shi,An, Xing-Lan,Zhang, Zi-Gang,Luo, Xiaoyan,Fossey, John S.,Deng, Wei-Ping
, p. 1156 - 1165 (2014)
A facile oxidative coupling of α-carbonyl radicals to 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) for the synthesis of 2,3-dicyanofurans and thiophenes starting from readily available β-diketones, simple ketones, and β-keto thioamides in up to 95% yield in one step was developed. Mechanistic investigations revealed that a radical process could be involved in this transformation, and a water promoted C-C bond cleavage pathway is proposed for the formation of 2,3-dicyanofurans and thiophenes.
