154740-93-9 Usage
General Description
4-azepan-1-yl-4-oxobutanoic acid, also known as DABOB or PVC-101, is a chemical compound that belongs to the class of gamma-aminobutyric acid (GABA) analogs. It is a synthetic compound that acts as a GABA receptor agonist, specifically targeting the GABA(A) receptor. DABOB has been studied for its potential as an anxiolytic agent, and has shown promising results in preclinical trials. It has also been investigated for its sedative and muscle relaxant properties. Additionally, DABOB has been explored as a potential tool for neuroscience research, specifically in the study of GABAergic neurotransmission. Overall, DABOB is a synthetic compound with potential therapeutic applications and research utility in the field of neuroscience.
Check Digit Verification of cas no
The CAS Registry Mumber 154740-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,7,4 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 154740-93:
(8*1)+(7*5)+(6*4)+(5*7)+(4*4)+(3*0)+(2*9)+(1*3)=139
139 % 10 = 9
So 154740-93-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H17NO3/c12-9(5-6-10(13)14)11-7-3-1-2-4-8-11/h1-8H2,(H,13,14)
154740-93-9Relevant articles and documents
Polycyclic aromatic compounds as anticancer agents: Structure-activity relationships of chrysene and pyrene derivatives
Banik, Bimal K,Becker, Frederick F
, p. 593 - 605 (2001)
A large number of diamides and diamines were synthesized using 6-amino chrysene and 1-amino pyrene as starting materials. A structure-activity study with cis-platinum as internal control against animal and human tumor lines was carried out in vitro. This study indicated that the in vitro cytotoxicity toward these lines depends on the functionality present in the molecules. The diamino compounds were found to be more potent than the diamides, and these were equally active irrespective of the end heterocyclic group whereas the activity of the diamides was strongly dependent on the terminal unit. In general, the diamides containing chrysene as the chromophore were more active than those with a pyrene ring. The size of the end heterocyclic ring, along with the nature of the spacer connecting the polycyclic ring to the heterocyclic ring, seemed to affect the biological activity in certain stabilizing agens. This agent also demonstrated the stabilizing agents. This agent also demonstrated the capacity to produce differentiation in leukemia cells lines.
