1547490-89-0Relevant articles and documents
Stereoselective synthesis of C-sulfonylated aziridines from halomethyl phenyl sulfone and N-tert-butanesulfinyl imines
Li, Ya,Huang, Haiji,Wang, Zhen,Yang, Fan,Li, Desheng,Qin, Bo,Ren, Xinfeng
, p. 969 - 973 (2014/01/06)
A highly efficient and stereoselective synthesis of C-sulfonylated aziridines is developed by using a one-step aza-Darzens reaction. When sodium bis(trimethylsilyl)amide (NaHMDS) was used as the base, bromomethyl phenyl sulfone reacted with N-tert-butanesulfinyl imines to afford the 2-sulfonylated aziridine products in very good yields and with stereoselectivities up to 50:1. The Royal Society of Chemistry 2014.