154812-31-4

Basic information

• Product Name: [(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 154812-31-4
• Molecular Weight: 423.555
• Mol File: 154812-31-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(154812-31-4)
• EPA Substance Registry System: [(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(154812-31-4)

Safety Data

• Hazardous Substances Data: 154812-31-4(Hazardous Substances Data)

Upstream product

• 2759-28-6 1-phenylmethylpiperazine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Relevant articles and documents

Synthesis and SAR of adatanserin: Novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT2 activity as potential anxiolytic and antidepressant agents

Several novel functionalized adamantyl aryl- and heteroarylpiperazine derivatives were prepared and examined in various receptor binding and behavioral tests to determine their serotonin receptor activities. Many compounds demonstrated modest to high affi

PIPERAZINE DERIVATIVES AS ANTIMALARIAL AGENTS

The invention relates to novel piperazine derivatives of formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria. wherein X represents -(CH2)o-2- or -C(=O)-; n represents the integer 0, 1 or 2; R1-R4 as described in claim 1