154877-60-8

Basic information

• Product Name: BUTTPARK 17\01-09
• Synonyms: BUTTPARK 17\01-09;1-{6-chloro-2-methylimidazo[1,2-a]pyridin-3-yl}ethan-1-one
• CAS NO: 154877-60-8
• Molecular Formula: C₁₀H₉ClN₂O
• Molecular Weight: 208.64426
• Mol File: 154877-60-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BUTTPARK 17\01-09(CAS DataBase Reference)
• NIST Chemistry Reference: BUTTPARK 17\01-09(154877-60-8)
• EPA Substance Registry System: BUTTPARK 17\01-09(154877-60-8)

Safety Data

• Hazardous Substances Data: 154877-60-8(Hazardous Substances Data)

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 1694-29-7 3-chloropentane-2,4-dione 
• 123-54-6 acetylacetone 

Downstream Products

• 1378022-70-8 3-[4-(6-Chloro-2-methyl-imidazo[1,2-a]pyridin-3-yl)-thiazol-2-ylamino]-4-isopropoxy-benzamide 

Relevant articles and documents

Double (amino-sulfur generation of formic acid ) - 1,3-propane diester compound and its synthetic method, pharmaceutical composition and use thereof

The invention relates to a bis(aminodithioformate)-1,3-propane diester compound, and synthesis method thereof, a pharmaceutical composition containing the compound and a use, and especially relates to the use in preparing drugs for treating or preventing cancers. The compound is represented as the formula (I), wherein A is selected from substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclic group, R1 and R2 are the same or different and are independently selected from hydrogen, alkyl, aryl alkyl or heteroaryl alkyl, or a substituted or unsubstituted heterocyclic ring formed together by the R1, the R2 and an N atom connected with the R1 and the R2.

Synthesis of imidazo[1,2-a]pyridines by the bis(acetyloxy)(phenyl)- λ3-iodane-Mediated oxidative coupling of 2-aminopyridines with β-keto esters and 1,3-diones

Imidazo[1,2-a]pyridine-3-carboxylates can be prepared directly from 2-aminopyridines and β-keto esters by using bis(acetyloxy)(phenyl)- λ3-iodane as an oxidant and boron trifluoride etherate as a catalyst. The amount of catalyst plays a key rol

Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110α inhibitor with an IC50 of 0.67 μM, through screening in a scintillation proximity assay. Optimization o