154956-79-3

Basic information

• Product Name: 3-(4-CHLOROPHENYL)-3-PYRROLIDINOL
• Synonyms: 3-(4-CHLOROPHENYL)-3-PYRROLIDINOL;3-(4-Chlorophenyl)-3-pyrrolidinol HCl;3-(4-chlorophenyl)pyrrolidin-3-ol hcl
• CAS NO: 154956-79-3
• Molecular Formula: C₁₀H₁₂ClNO
• Molecular Weight: 197.664
• Mol File: 154956-79-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-CHLOROPHENYL)-3-PYRROLIDINOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-CHLOROPHENYL)-3-PYRROLIDINOL(154956-79-3)
• EPA Substance Registry System: 3-(4-CHLOROPHENYL)-3-PYRROLIDINOL(154956-79-3)

Safety Data

• Hazardous Substances Data: 154956-79-3(Hazardous Substances Data)

Upstream product

• 96431-51-5 3-(4-chloro-phenyl)-3-hydroxy-pyrrolidine-1-carboxylic acid ethyl ester 
• 324785-29-7 tert-butyl 3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 

Downstream Products

• 1021171-18-5 C₁₈H₂₅ClN₂O₃ 
• 1233228-26-6 5-Chloro-2-{3-[3-(4-chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-propoxy}-4-methoxy-benzoic acid methyl ester 
• 1136651-04-1 3-(4-chlorophenyl)-1-[2-(1H-indol-3-yl)ethyl]pyrrolidin-3-ol 
• 1136651-10-9 3-(4-chlorophenyl)-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)pyrrolidin-3-ol 
• 1136651-03-0 3-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)pyrrolidin-3-ol 

Relevant articles and documents

NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS

The present invention relates to novel morpholine, oxazapane and piperidine derivatives that act as ligands for CC chemokine receptors, such as CCR1. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

Haloperidol analogs

Haloperidol analogs that conforms to the structural formulae: wherein: R is H, or —(CH2)n—OH, n is an integer from 0 to 2, and A is a heterocyclic bridging group, consisting essentially of carbon and at least one nitrogen atom, which effectively maintains the distance between the moieties connected thereby such that the compound (1) is incapable of metabolizing to BCPP+ like species, (2) has an affinity for the D2 receptor subtype of 151 is H, or —(CH2)n—OH, n is an integer from 0 to 2, B is an aza- or diaza-bicyclo group, which effectively maintains the distance between the moieties connected thereby such that the compound is incapable of metabolizing to BCPP+ like species; and Z is —CH— or N; and pharmaceutically acceptable salts, esters, derivatives, metal complexes, conjugates and prodrugs thereof.