154989-45-4 Usage
General Description
7-ETHYL-1H-INDOLE-3-CARBALDEHYDE is a chemical compound with the molecular formula C11H11NO. It is a derivative of indole, which is a heterocyclic compound that is commonly found in natural products and pharmaceuticals. This specific compound is an aldehyde derivative of indole, with an ethyl group attached to the nitrogen atom at the 7th position. It is commonly used as an intermediate in the synthesis of various organic compounds and pharmaceuticals, due to its versatile reactivity and functional group. Its chemical structure and properties make it a valuable building block for the production of complex molecules in organic synthesis. Additionally, it has potential applications in the field of medicinal chemistry for the development of new drugs and bioactive compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 154989-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,9,8 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 154989-45:
(8*1)+(7*5)+(6*4)+(5*9)+(4*8)+(3*9)+(2*4)+(1*5)=184
184 % 10 = 4
So 154989-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO/c1-2-8-4-3-5-10-9(7-13)6-12-11(8)10/h3-7,12H,2H2,1H3
154989-45-4Relevant articles and documents
A facile approach to tryptophan derivatives for the total synthesis of argyrin analogues
Chen, Chou-Hsiung,Genapathy, Sivaneswary,Fischer, Peter M.,Chan, Weng C.
supporting information, p. 9764 - 9768 (2015/01/09)
A facile route has been established for the synthesis of indole-substituted (S)-tryptophans from corresponding indoles, which utilizes a chiral auxiliary-facilitated Strecker amino acid synthesis strategy. The chiral auxiliary reagents evaluated were (S)-methylbenzylamine and related derivatives. To illustrate the robustness of the method, eight optically pure (S)-tryptophan analogues were synthesized, which were subsequently used for the convergent synthesis of a potent antibacterial agent, argyrin A and its analogues.
NBu4NI-catalyzed C3-formylation of indoles with N-methylaniline
Li, Lan-Tao,Huang, Juan,Li, Hong-Ying,Wen, Li-Juan,Wang, Peng,Wang, Bin
supporting information; experimental part, p. 5187 - 5189 (2012/06/01)
nBu4NI-catalyzed C3-selective formylation of N-H and N-substituted indoles by using N-methylaniline as a formylating reagent was first successfully demonstrated.
