1550-09-0

Basic information

• Product Name: 1-Chloro-6-fluorohexane
• Synonyms: 1-Chloro-6-fluorohexane;1-fluoro-6-chlorohexane
• CAS NO: 1550-09-0
• Molecular Formula: C₆H₁₂ClF
• Molecular Weight: 138.6109
• Mol File: 1550-09-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 160°C (estimate)
• Flash Point: 43.8°C
• Appearance: /
• Density: 1.0150
• Vapor Pressure: 4.29mmHg at 25°C
• Refractive Index: 1.4168
• CAS DataBase Reference: 1-Chloro-6-fluorohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-6-fluorohexane(1550-09-0)
• EPA Substance Registry System: 1-Chloro-6-fluorohexane(1550-09-0)

Safety Data

• Hazardous Substances Data: 1550-09-0(Hazardous Substances Data)

Usage

General Description

1-Chloro-6-fluorohexane is a chemical compound with the molecular formula C6H12ClF. It is a colorless liquid with a strong odor, and is often used in industrial processes as a solvent or in the production of other chemicals. 1-Chloro-6-fluorohexane is considered to be a halogenated alkane, as it contains both chlorine and fluorine atoms. It is important to handle 1-Chloro-6-fluorohexane with care, as it is known to be a skin and eye irritant and may have harmful effects if inhaled. Additionally, it is important to note that 1-Chloro-6-fluorohexane may be harmful to aquatic life, making proper disposal and handling crucial.

InChI:InChI=1/C6H12ClF/c7-5-3-1-2-4-6-8/h1-6H2

Upstream product

• 1361022-62-9 2-(6-chlorohexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 928-89-2 6-chlorohexene 
• 71042-21-2 4-methylbenzenesulfonic acid 6-chlorohexyl ester 
• 2009-83-8 6-chloro-1-hexanol 
• 4779-64-0 2-(6-chloro-hexyl)-1,1-diphenyl-isourea; hydrofluoride 
• 2163-00-0 1,6-dichlorohexane 
• 373-32-0 6-fluoro-hexan-1-ol 

Downstream Products

• 334-28-1 7-fluoro-heptanoic acid 
• 408-27-5 8-fluoro-octan-1-ol 
• 373-30-8 1-fluoro-6-iodohexane 
• 3109-58-8 16-fluorohexadecanoic acid 
• 408-15-1 8-fluoro-oct-1-yne 
• 459-95-0 7-fluoro-heptanoic acid ethyl ester 

Relevant articles and documents

Nickel-Catalyzed Dimerization and Alkylarylation of 1,3-Dienes with Alkyl Fluorides and Aryl Grignard Reagents

In the presence of a nickel catalyst, 1,3-butadiene undergoes selective dimerization and alkylarylation with alkyl fluorides and aryl Grignard reagents to give 1,6-octadienes with alkyl and aryl groups at the 3- and 8-positions, respectively, by the consecutive formation of three carbon-carbon bonds. The formation of an anionic nickel complex plays an important role in forming C-C bonds with alkyl fluorides.

A useful conversion of alcohols to alkyl fluorides

A useful conversion of alcohols to alkyl fluorides via their fluoroformates is introduced. The fluoroformates are obtained in nearly quantitative yield from the alcohols by treatment with COF2 (generated in situ from bis(trichloromethyl) carbonate) in ether with KF as an added acid scavenger. The neat fluoroformates are cleaved to the fluorides by heating at 120-125°C using hexabutylguanidinium fluoride (HBGF) as the catalyst.

FLUORINATION OF HALOGENO ALCOHOLS WITH 1,1,2,3,3,3-HEXAFLUOROPROPYL DIETHYLAMINE

Fluorination of halogeno alcohols with 1,1,2,3,3,3-hexafluoropropyl diethylamine (PPDA) was investigated. 2-Bromo-1-fluorobutane was obtained from the reaction of PPDA and 2-bromo-1-butanol (yield 50percent).Similar results were obtained from other alipha