155003-35-3

Upstream product

• 18643-50-0 1-pentynyl lithium 
• 138436-31-4 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-propionaldehyde 

Downstream Products

• 155003-37-5 (Z)-(S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-oct-4-en-3-one 
• 155003-36-4 (E)-(S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-oct-4-en-3-one 
• 155003-39-7 (S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-hydroxymethyl-oct-4-yn-3-one 

Relevant academic research and scientific papers

Protecting group controlled diastereoselective reduction of diprotected α,α-bis(hydroxymethyl) ketones derived from THYM*, using the DIBALH / MgBr2 system

The reduction of diprotected α,α-bis(hydroxymethyl)ketones 5, derived from the novel chiral building blocks THYM*1 and BHYMA*2 has been realized with good to excellent stereoselectivity (from 85:15 to 97:3), through a appropriate choice of the two protect