155003-67-1

Basic information

• Product Name: (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-propan-1-ol
• CAS NO: 155003-67-1
• Molecular Weight: 464.677
• Mol File: 155003-67-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-propan-1-ol(155003-67-1)
• EPA Substance Registry System: (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-propan-1-ol(155003-67-1)

Safety Data

• Hazardous Substances Data: 155003-67-1(Hazardous Substances Data)

Upstream product

• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 

Downstream Products

• 155003-28-4 (S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-heptan-3-one 
• 155003-68-2 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethyl)-propionaldehyde 

Relevant articles and documents

Asymmetric synthesis of all 8 stereoisomers of α-methyl homoallylic alcohols derived by crotyl addition onto bis(hydroxymethyl)acetaldehydes (BHYMA*)

The asymmetric synthesis of epimeric α-methyl homoallylic alcohols 4 and 7 has been realized respectively through chelation-controlled addition of crotylbutyltin to asymmetrized bis(hydroxymethyl) acetaldehydes (BHYMA*) 3, and via chelation-controlled reduction of ketones 8. Due to the stereochemical flexibility of the C-5 chiral centre and to the enantiodivergent preparation of both anantiomers of 3, all 8 isomers of these crotylation products become accessible, starting from an unique precursor 1.