15507-27-4

Usage

Uses

Used in Pharmaceutical Industry:
2-[2-(2H-benzimidazol-2-ylidene)hydrazino]-1H-benzimidazole is used as a potential active pharmaceutical ingredient for its potential antiparasitic, antibacterial, or antifungal properties. Its complex molecular structure and the presence of the hydrazine functional group suggest that it may exhibit biological activity that could be harnessed for therapeutic purposes.
Used in Chemical Research:
2-[2-(2H-benzimidazol-2-ylidene)hydrazino]-1H-benzimidazole is used as a subject of chemical research for its potential reactivity and the possibility of further chemical modifications and derivatization. 2-[2-(2H-benzimidazol-2-ylidene)hydrazino]-1H-benzimidazole's unique structure may allow for the development of new chemical entities with enhanced properties or novel applications in various fields.
Used in Drug Development:
2-[2-(2H-benzimidazol-2-ylidene)hydrazino]-1H-benzimidazole is used as a starting point for drug development, where its potential biological activity and reactivity can be explored and optimized to create new therapeutic agents. Further research and investigation into the compound's properties and potential applications may lead to the discovery of new drugs with improved efficacy and safety profiles.

Upstream product

• 934-32-7 1H-benzimidazol-2-amine 

Relevant academic research and scientific papers

4,4'-Azopyridine as an easily prepared and recyclable oxidant for synthesis of symmetrical disulfides from thiols or alkyl halides(tosylates)/thiourea

Heterocyclic azo compounds, prepared from corresponding amines in one step, are used as effective oxidants for the conversion of thiols into symmetrical disulfides in high yields. Among the studied azo compounds, 4,4'-azopyridine was found to be very efficient for the odorless conversion of alkyl halides into disulfides in the presence of thiourea. An attractive feature of this azo compound is that its obtained solid side product hydrazine is easily separated by filtration and can be recycled to its azo compound for further use.

5,5′-Dimethyl-3,3′-azoisoxazole as a new heterogeneous azo reagent for esterification of phenols and selective esterification of benzylic alcohols under Mitsunobu conditions

5,5′-Dimethyl-3,3′-azoisoxazole is used as a new efficient heterogeneous azo reagent for the highly selective esterification of primary and secondary benzylic alcohols and phenols with aliphatic and aromatic carboxylic acids via Mitsunobu protocols. The reaction is highly selective for primary benzylic alcohols versus secondary ones, aliphatic alcohols and also phenols. The isoxazole hydrazine byproduct can be simply isolated by filtration and recycled to its azoisoxazole by oxidation.

Electrochemical oxidation of 2-aminobenzimidazole at pyrolytic graphite electrode

The electrochemical oxidation of 2-aminobenzimidazole (2-ABT) has been studied in aqueous solution in a wide pH range of 3.0 to 10.8 using a pyrolytic graphite electrode.The initial step in the oxidation at physiological pH involves a 1e, 1H+ reaction leading to the formation of a free radical species, which rapidly dimerizes to give hydrazo intermediate.Further oxidation of hydrazo species in a 2e, 2H+ reaction leads to the formation of azobenzimidazole.Alternatively, the 1e, 1H+ oxidation of protonated 2-ABT gives a cation free radical, which on loss of proton followed by disproportionation gives s-tetrazine derivative of 2-ABT.Both the products have been isolated and characterized. keywords: oxidation / 2-aminobenzimidazole / electrochemistry