155089-05-7

Upstream product

• 1026174-62-8 2-[(5E,7E)-(S)-9-tert-Butoxycarbonylamino-4-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-6-methyl-nona-5,7-dienyl]-oxazole-4-carboxylic acid ethyl ester 
• 142841-00-7 2-[bromomethyl]-4-oxazolecarboxylic acid ethyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 155089-00-2 ((2E,4E)-4-Methyl-6-oxo-hexa-2,4-dienyl)-carbamic acid tert-butyl ester 
• 155089-04-6 [(2E,4E)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-8-oxo-octa-2,4-dienyl]-carbamic acid tert-butyl ester 
• 155089-03-5 [(2E,4E)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-7-(methoxy-methyl-carbamoyl)-4-methyl-hepta-2,4-dienyl]-carbamic acid tert-butyl ester 
• 155088-99-6 (2E,4E)-6-tert-Butoxycarbonylamino-3-methyl-hexa-2,4-dienoic acid ethyl ester 
• 155088-97-4 [(2E,4E)-(S)-6-Hydroxy-8-((S)-4-isopropyl-2-oxo-oxazolidin-3-yl)-4-methyl-8-oxo-octa-2,4-dienyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of the Oxazole- and Diene-Containing C9-C23 Fragment of the Type A Streptogramin Antibiotics

The right-hand portion (3) of the type A streptogramin antibiotics was synthesized in non-racemic from through use of a Horner-Wadsworth-Emmons reaction for diene construction, an asymmetric aldol condensation, and a zinc-promoted oxazole addition reactio