155090-97-4

Basic information

• Product Name: 2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI)
• Synonyms: 2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI);1,4-DIMETHYL-3-SULFANYLPIPERAZINE-2,5-DIONE
• CAS NO: 155090-97-4
• Molecular Formula: C6 H10 N2 O2 S
• Molecular Weight: 174.22
• Product Categories: PIPERIDINE
• Mol File: 155090-97-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI)(155090-97-4)
• EPA Substance Registry System: 2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI)(155090-97-4)

Safety Data

• Hazardous Substances Data: 155090-97-4(Hazardous Substances Data)

Usage

Chemical compound

2,5-Piperazinedione,3-mercapto-1,4-dimethyl-(9CI)

Family

Piperazine

Contains

sulfur atom, two methyl groups

Uses

Organic synthesis, building block for pharmaceuticals and agrochemicals, materials science, precursor for novel organic compounds

Potential

Biological activities, research and development in pharmaceutical industry

Upstream product

• 130806-25-6 3-bromosarcosine anhydride 
• 5076-82-4 sarcosine anhydride 
• 155090-96-3 3-acetylthio-1,4-dimethylpiperazine-2,5-dione 

Relevant articles and documents

Synthesis and Activity of New Epipolythiopiperazine-2,5-dione Compounds. I

The new lipophilic epipolythiopiperazine-2,5-diones 1,4-dibutylepidithiopiperazine-2,5-dione, 1,4-dibenzylepidithiopiperazine-2,5-dione, 1-benzyl-4-methylepidithiopiperazine-2,5-dione and 3,3'-dithiobis(1,4-dimethylpiperazine-2,5-dione) were synthesized.Unlike the parent compound, the fungal toxin and immunomodulating agent gliotoxin, these compounds did not affect macrophage adherence and cell proliferation in vitro.Like the reduced form of gliotoxin and other simple analogues, these new compounds induce oxidative damage to naked DNA.We conclude that an increase in lipophilicity plays no part in the biological activity of these compounds and in fact abrogates almost all activity.We also synthesized an intermolecular disulfide analogue which also lacked activity.