1551-16-2

Basic information

• Product Name: 3-ETHYL-1H-PYRROLE
• Synonyms: 3-ETHYL-1H-PYRROLE;1H-Pyrrole, 3-ethyl-
• CAS NO: 1551-16-2
• Molecular Formula: C₆H₉N
• Molecular Weight: 95.14
• Mol File: 1551-16-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 158.7°Cat760mmHg
• Flash Point: 53.2°C
• Appearance: /
• Density: 0.945g/cm³
• Vapor Pressure: 3.36mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: 3-ETHYL-1H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHYL-1H-PYRROLE(1551-16-2)
• EPA Substance Registry System: 3-ETHYL-1H-PYRROLE(1551-16-2)

Safety Data

• Hazardous Substances Data: 1551-16-2(Hazardous Substances Data)

Usage

General Description

3-ETHYL-1H-PYRROLE is an organic compound consisting of a pyrrole ring with an ethyl group attached to the third carbon atom. It belongs to the class of heterocyclic aromatic compounds and is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is also found in some natural products and has been identified as a component of the scent of certain flowers. 3-ETHYL-1H-PYRROLE is known for its characteristic odor and has been used in the fragrance industry as a component of perfumes and flavoring agents. Additionally, it has potential applications in the field of materials science, particularly in the development of organic semiconductors for electronics and optoelectronic devices. Overall, 3-ETHYL-1H-PYRROLE is a versatile chemical with various industrial and research applications.

InChI:InChI=1/C6H9N/c1-2-6-3-4-7-5-6/h3-5,7H,2H2,1H3

Upstream product

• 66414-04-8 diethyl 3-ethyl-5-methylpyrrole-2,4-carboxylate 
• 81453-98-7 3-acetyl-1-(phenylsulfonyl)pyrrole 
• 106058-85-9 1-(1-tosyl-1H-pyrrol-3-yl)ethan-1-one 
• 1260827-11-9 methyl 4-ethyl-1H-pyrrole-3-carboxylate 
• 860759-68-8 4-ethyl-5-methyl-pyrrole-2,3-dicarboxylic acid-3-ethyl ester 
• 111468-98-5 2,4,5-triiodo-3-acetylpyrrole 
• 97188-23-3 3-ethyl-1-phenylsulfonylpyrrole 
• 201230-82-2 carbon monoxide 
• 71580-34-2 3-vinyl-1H-pyrrole 
• 117270-78-7 N-(triisopropylsilyl)-3-ethylpyrrole 
• 52866-26-9 ((E)-Buta-1,3-dienyl)-diethyl-amine 
• 109-97-7 pyrrole 
• 14936-94-8 ethyl cation 
• 1072-82-8 3-acetylpyrrole 

Downstream Products

• 111495-43-3 2-ethyl-1,4-bis<(benzyloxycarbonyl)amino>butane 
• 97188-23-3 3-ethyl-1-phenylsulfonylpyrrole 
• 63009-16-5 2-ethyltetramethylenediamine 
• 355114-76-0 3-ethyl-1-(2-methyl-2-propenyl)pyrrole 
• 1326240-86-1 rac-8-ethyl-1-phenyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine 
• 1326240-87-2 rac-7-ethyl-1-phenyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine 
• 97188-34-6 2-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole 
• 97188-35-7 4-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole 
• 97188-36-8 5-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole 
• 97188-37-9 2-acetyl-3-ethylpyrrole 
• 97188-45-9 2-acetyl-4-ethylpyrrole 

Relevant articles and documents

Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision**

We report the first cellular application of the emerging near-quantitative photoswitch pyrrole hemithioindigo, by rationally designing photopharmaceutical PHTub inhibitors of the cytoskeletal protein tubulin. PHTubs allow simultaneous visible-light imaging and photoswitching in live cells, delivering cell-precise photomodulation of microtubule dynamics, and photocontrol over cell cycle progression and cell death. This is the first acute use of a hemithioindigo photopharmaceutical for high-spatiotemporal-resolution biological control in live cells. It additionally demonstrates the utility of near-quantitative photoswitches, by enabling a dark-active design to overcome residual background activity during cellular photopatterning. This work opens up new horizons for high-precision microtubule research using PHTubs and shows the cellular applicability of pyrrole hemithioindigo as a valuable scaffold for photocontrol of a range of other biological targets.

Synthesis process method of 3-substituted-1H-pyrrole

The invention provides a synthetic process method of a 3-substituted-1H-pyrrole compound. The process method comprises the following steps: by taking diethylamine hydrochloride and glycine ethyl esterhydrochloride as initial raw materials, respectively carrying out Mannich reaction and sulfamide reaction, and carrying out cyclization reaction, dehydration thinning reaction, aromatization reactionand hydrolysis decarboxylation reaction to obtain a 3-substituted-1H-pyrrole compound. According to the synthesis process method of the 3-substituted-1H-pyrrole compound, the whole synthesis route isgood in step repeatability, mild in operation condition and high in safety, and large-scale production and industrial popularization are facilitated; post-treatment energy consumption is low, a largeamount of toxic wastewater is not generated, no pollution is caused to the environment, the production safety level and the production cost are reduced, application of green and environment-friendlyindustrial production is facilitated, and wide application prospects are achieved.

Synthesis of 2,2′-bipyrrole-5-carboxaldehydes and their application in the synthesis of B-ring functionalized prodiginines and tambjamines

Facile, versatile, and cost-effective synthetic routes for the preparation of a range of new 3-alkyl-, 4-alkyl-, 3,4-dialkyl-, and 3-halo-4-alkyl-2, 2′-bipyrrole-5-carboxaldehydes have been developed. These 2,2′-bipyrrole-5-carboxaldehydes offer interesting potential as building blocks for making bioactive natural and unnatural products, as demonstrated by the synthesis of B-ring functionalized prodiginines (PGs) and tambjamines.