155100-96-2Relevant academic research and scientific papers
Production of a New Type of Bioactive Phenolic Compound
Kobayashi, Akio,Koguchi, Yutaka,Kanzaki, Hiroshi,Kajiyama, Shin-ichiro,Kawazu, Kazuyoshi
, p. 133 - 134 (2007/10/02)
Peroxidase (POD) catalyzed the polymerization of naturally occurring phenolics to give a variety of bioactive products.The guaiacol readily reacted in the POD system and afforded potential anti-microbial compounds.Three active phenols, 1, 2, and 3, were isolated from the reaction mixture.Spectroscopic analyses elucidated that 1 and 2 were a dimer and a trimer respectively originating from guaiacol.Compound 3 was readily oxidized to 4 by exposure to air.The structure of 4 was determined by a combination of chemical modification and spectroscopic analyses, and 3 was elucidated to be the hydroxyquinoe form of 4.
