155106-26-6

Basic information

• Product Name: (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine
• Synonyms: (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine
• CAS NO: 155106-26-6
• Molecular Weight: 331.412
• Mol File: 155106-26-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine(155106-26-6)
• EPA Substance Registry System: (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine(155106-26-6)

Safety Data

• Hazardous Substances Data: 155106-26-6(Hazardous Substances Data)

Upstream product

• 62012-14-0 1-(3-acetoxypropyl)pyrrolidin-2-one 
• 62012-15-1 1-(3-hydroxypropyl)pyrrolidin-2-one 
• 126524-09-2 2-bromo-1-(2-methoxy-6-methylphenyl)ethanone 
• 155106-23-3 3-(2-thioxo-1-pyrrolidinyl)propyl acetate 

Downstream Products

• 155106-27-7 (E)-1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine 
• 72473-04-2 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine 

Relevant articles and documents

Formal synthesis of two Elaeocarpus alkaloids: elaeocarpine and isoelaeocarpine

1-(3-Acetoxypropyl)pyrrolidine-2-thione 7, prepared by acetylation and thionation of the readily accessible 1-(3-hydroxypropyl)pyrrolidin-2-one 5, undergoes Eschenmoser alkylidenation (sulfide contraction) with two phenacyl bromides to give the vinylogous amides (E)-1-(3-acetoxypropyl)-2-benzoylmethylenepyrrolidine 8 and the corresponding 2-methoxy-6-methylbenzoyl analogue 14.Reduction of the latter with lithium aluminium hydride yields 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine 12, thereby completing a formal synthesis of the Elaeocarpus alkaloids elaeocarpine 10 and isoelaeocarpine 11.