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4-Methoxy-2-(phenylthio)aniline is an organic compound with the chemical formula C13H13NOS. It is a derivative of aniline, featuring a 4-methoxy group and a phenylthio group attached to the 2-position of the aniline molecule. 4-methoxy-2-(phenylthio)aniline is characterized by its yellow crystalline appearance and is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of various dyes, pharmaceuticals, and agrochemicals. Due to its chemical structure, it exhibits properties such as reactivity towards electrophilic substitution and the ability to form charge-transfer complexes. The compound's synthesis typically involves the reaction of 2-aminophenol with phenyl disulfide in the presence of a base, followed by methylation. It is important to handle 4-methoxy-2-(phenylthio)aniline with care due to its potential toxicity and reactivity.

1552-18-7

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1552-18-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1552-18-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,5 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1552-18:
(6*1)+(5*5)+(4*5)+(3*2)+(2*1)+(1*8)=67
67 % 10 = 7
So 1552-18-7 is a valid CAS Registry Number.

1552-18-7Relevant academic research and scientific papers

FeF3/i2-catalyzed synthesis of 4-chalcogen- substituted arylamines by direct thiolation of an arene C-H bond

Fang, Xiao-Li,Tang, Ri-Yuan,Zhang, Xing-Guo,Li, Jin-Heng

experimental part, p. 1099 - 1105 (2011/05/14)

An efficient regioselective synthesis of 4-chalcogen-substituted-arylamines by FeF3-catalyzed sulfenylation and selenation of arylamines has been developed. In the presence of FeF3and I2, a variety of arylamines underwent the reaction with disulfides or diselenides to afford the corresponding 4-sulfenyl-or 4-selenenyl-arylamines in moderate to good yields. Georg Thieme Verlag Stuttgart.

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