155220-56-7Relevant academic research and scientific papers
Application of the thioimidate cyclopropane rearrangement to heterocyclic synthesis. Preparation of diaryl pyrrolines
Chang, Ronald K.,Dipardo, Robert M.,Kuduk, Scott D.
, p. 8513 - 8516 (2005)
Substituent effects on the thioimidate cyclopropane rearrangement and factors affecting regioselectivity are reported. Palladium-mediated coupling of the pyrrolothiomethylimidate rearrangement products with Grignard reagents provides diaryl pyrrolines in
A General Stereocontrolled Synthesis of cis-2,3 Disubstituted Pyrrolidines and Piperidines
Pal, Kollol,Behnke, Mark L.,Tong, Liang
, p. 6205 - 6208 (2007/10/02)
A general synthetic method is reported for the preparation of cis-2,3-disubstituted pyrrolidines and piperidines from readily available acyclic precursors.The key reaction involves the stereoselective reduction of a cyclic imine controlled by the C-3 subs
