155225-20-0Relevant articles and documents
General and versatile approach to the synthesis of optically active 5-alkylpiperazine-2-carboxylic acids
Falorni,Giacomelli,Satta,Cossu
, p. 391 - 395 (1994)
General and convenient syntheses of optically active 5-alkylpiperazine-2-carboxylic acids are described. The methods are based on cyclization of L- or D-serine with α-amino acids and occur without loss of optical purity. The presented procedures are based
Chiral Ligands Containing Heteroatoms. 11. Optically Active 2-Hydroxymethyl Piperazines as Catalyst in the Enantioselective Addition of Diethylzinc to Benzaldehyde
Falorni, Massimo,Satta, Michele,Conti, Sandra,Giacomelli, Giampaolo
, p. 2389 - 2398 (2007/10/02)
Starting from enantiomerically pure serine, a series of (2R,5S) and (2S,5S)-2-hydroxymethyl-5-alkyl piperazines 1-5 were prepared in good yields without any racemization.The use of these compounds as chiral catalysts for the enantioselective addition of d