155236-67-2

Upstream product

• 138760-89-1 (Z)-(S)-2-(Acetoxymethyl)hept-3-en-1-ol 
• 76-83-5 trityl chloride 
• 138760-94-8 (R)-2-(triphenylmethyloxymethyl)-3(Z)-hepten-1-ol 

Downstream Products

• 138761-09-8 (4S,5S)-4-Butyl-2,2-dimethyl-5-trityloxymethyl-[1,3]dioxane 

Relevant academic research and scientific papers

Stereoselective epoxidation of asymmetrized 2-alkenyl-1,3-propanediols

Asymmetrized 2-alkenyl 1,3-propanediols are stereoselectively epoxidized to the same main diastereoisomer both with 3-chloroperbenzoic acid and the VO(acac)2/t-butyl hydroperoxyde system. Using the latter epoxidating reagent in combination with a protection-deprotection sequence involving the two homoallylic hydroxy groups, all the four cis epoxides were easily achieved in stereoisomeric pure from starting from a single common (Z) precursor.