155282-51-2Relevant articles and documents
Large-scale preparation of long-chain ADMET synthons
Sauty, Nicolas F.,Li, Hong,Da Silva, Lucas Caire,Wagener, Kenneth B.
, p. 2409 - 2415 (2014)
We report a convenient process with minimal purification to produce large quantities of α,ω-alkenyl alcohols. These reagents are indispensable precursors in ADMET chemistry. Icos-19-en-1-ol, nonacos-28-en-1-ol, and octatriacont-37-en-1-ol were produced effortlessly in large quantities (up to 45 g in a single batch) from undec-10-en-1-ol. By extension of the method, any desired methylene run length in the ADMET precursor can be achieved. Copyright