155295-65-1Relevant articles and documents
NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS
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Page/Page column 49, (2011/12/14)
The present invention is directed to novel compounds of formula (I) and their use in treating metabolic diseases.
Novel small renin inhibitors containing 4,5- or 3,5-Dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2-P3 sites
Jung, Grace L.,Anderson, Paul C.,Bailey, Murray,Baillet, Monique,Bantle, Gary W.,Berthiaume, Sylvie,Lavallee, Pierre,Llinas-Brunet, Montse,Thavonekham, Bounkham,Thibeault, Diane,Simoneau, Bruno
, p. 2317 - 2336 (2007/10/03)
Renin inhibitors containing a 4,5- or a 3,5-dihydroxy-2-substituted-6-phenylhexanamide fragment at the P2-P3 sites have been prepared and evaluated. The four possible diastereomeric diols of the two series of inhibitors were synthesi