15533-10-5Relevant academic research and scientific papers
Aroyl hydrazone with large Stokes shift as a fluorescent probe for detection of Cu2+ in pure aqueous medium and in vivo studies
Chauhan, Brijesh Singh,Choudhury, Lokman H.,Dwivedi, Romi,Panday, Anoop Kumar,Singh, Saumya,Singh, Vinod Prasad,Srikrishna, S.
, (2020)
An aroyl hydrazone based fluorescent probe, hpsh, has been developed for the selective detection of Cu2+ ions in pure aqueous medium by static fluorescence quenching. The fluorescence quenching of hpsh in the presence of Cu2+ takes place as a result of ground state complex formation through intramolecular charge transfer (ICT). Addition of Cu2+ ions changes the color of the solution from colorless to yellow-green which is clearly visible by naked eye. Large Stokes shift of hpsh prevents the self-quenching of the probe in absence of metal ions. The observed stoichiometry between Cu2+ and probe has been found as 1:2 (M: L). MTT assay of hpsh on fruit flies confirms that the probe is non-toxic and biocompatible. The plausible in vivo bioimaging application of the probe to detect Cu2+ in Drosophila gut tissues as well as in adult fruit fly has been investigated with excellent results.
Synthesis, structural and corrosion inhibition studies on Mn(II), Cu(II) and Zn(II) complexes with a Schiff base derived from 2-hydroxypropiophenone
Mishra, Monika,Tiwari, Karishma,Singh, Ashish Kumar,Singh, Vinod P.
, p. 57 - 65 (2014/05/20)
A Schiff base, 2-hydroxy-benzoic acid [1-(2-hydroxy-phenyl)-propylidene]- hydrazide (H2hbpp) and its Mn(II), Cu(II) and Zn(II) complexes have been synthesized. These compounds have been characterized by different physico-chemical and spectroscopic techniques (UV-Vis, IR, NMR and ESI-Mass). The molecular structure of H2hbpp and its Mn(II) and Zn(II) complexes are determined by single crystal X-ray diffraction technique. In Mn(II) and Cu(II) complexes, the ligand coordinates through azomethine-N, carbonyl-O and phenolate-O (2-hydroxypropiophenone) forming a mono-nuclear 6-coordinate distorted octahedral geometry around metal. However, Zn(II) complex forms a phenoxo-bridged centrosymmetric dimer with 5-coordinate distorted square pyramid geometry around each metal ion. In this complex, the ligand bonds through azomethine-N, carbonylate-O and two phenolate-O, and a DMSO molecule occupies one of the vacant site of each metal. The structure of Cu(II) complex has been satisfactorily modeled by density functional theory (DFT) and time dependent-DFT (TD-DFT) calculations. The corrosion inhibition study of the synthesized compounds for mild steel in 1 M HCl medium has also been performed and the activity is found in the order: H2hbpp Cu(II) complex Mn(II) complex Zn(II) complex.
