15548-43-3

Usage

Uses

Used in Pharmaceutical Industry:
Mannobiose is used as a pharmaceutical compound for its potential therapeutic applications. It can be utilized in the development of drugs targeting specific biological processes due to its unique structural properties and interactions with other molecules.
Used in Biochemical Research:
In the field of biochemical research, mannobiose serves as an important tool for studying carbohydrate metabolism, enzyme activity, and the structural analysis of complex carbohydrates. Its presence in various plant sources makes it a valuable subject for understanding the biosynthesis and function of carbohydrates in living organisms.
Used in Food Industry:
Mannobiose can be used as an ingredient in the food industry, particularly in the development of novel sweeteners or as a component in the formulation of functional foods. Its unique properties may contribute to the enhancement of taste, texture, or nutritional value of certain food products.
Used in Cosmetics Industry:
In the cosmetics industry, mannobiose may find applications in the development of skincare products, where it can potentially be used for its moisturizing, anti-aging, or skin-soothing properties. Its ability to interact with other molecules may contribute to the effectiveness of cosmetic formulations.

InChI:InChI=1/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8+,9+,10-,11u,12+/m1/s1

Upstream product

• 6401-81-6 mannotriose 
• 1263-76-9 O-β-D-mannopyranosyl-(1-4)-O-β-D-mannopyranosyl-(1-4)-O-β-D-mannopyranosyl-(1-4)-D-mannopyranose 

Related news

Regioselective synthesis of mannobiose (cas 15548-43-3) and mannotriose by reverse hydrolysis using a novel 1,6-α-d-mannosidase from Aspergillus phoenicis09/03/2019

A novel 1,6-α-d-mannosidase was produced by Aspergillus phoenicis grown on a commercial manno-oligosaccharide preparation in liquid culture. The enzyme hydrolysed only α-d-Manp-(1→6)-d-Manp and did not act on α-d-Manp-(1→2)-d-Manp, or α-d-Manp-(1→3)-d-Manp. The 1,6-α-d-mannosidase was us...detailed

Short communicationβ 1-4 mannobiose (cas 15548-43-3) enhances Salmonella-killing activity and activates innate immune responses in chicken macrophages08/31/2019

Salmonella spp. is one of the major causes of food-borne illness in humans, and Salmonella enteritidis (SE) infection in commercial poultry is a world-wide problem. Here we have investigated the in vitro immune-modulating effects of β 1-4 mannobiose (MNB), which was previously found to prevent ...detailed

ORIGINAL ARTICLETherapeutic Effects of β1, 4 mannobiose (cas 15548-43-3) in a Balb/c Mouse Model of Intranasally-Induced Pollen Allergy08/29/2019

ABSTRACTBackground: Nutritional prebiotic supplementation represents an attractive approach for interventions of allergy. In this study, the potential therapeutic effect of β-1, 4 mannobiose (MNB) in a murine model of cedar polli- nosis was investigated.Methods: Groups of Balb/c mice were intra...detailed

Relevant academic research and scientific papers

Oxidation of mannosyl oligosaccharides by hydroxyl radicals as assessed by electrospray mass spectrometry

The hydroxyl radicals are widely implicated in oxidation of carbohydrates during biological and industrial processes being responsible for their structural modifications and causing functional damage. The identification of intermediate oxidation products is hampered by a lack of reliable sensible methods for their detection. In this study, the oxidation of two models of galactomannans (Man3 and GalMan2) has been studied in reaction with hydroxyl radical generated by Fenton reaction. The oxidation patterns were assessed using preparative ligand-exchange/size-exclusion chromatography (LEX/SEC) coupled with tandem electrospray mass spectrometry (ESI-MS/MS). This allowed the identification of derived oligosaccharides (OS) containing hexuronic, hexonic, pentonic and erythronic acid residues and neutral OS bearing hydroperoxy, hydrated carbonyl moieties and residues from pyranosyl ring cleavage. The depolymerization products have been also detected upon oxidation of oligomers. This study allowed developing a simple, effective 'fingerprinting' protocol for detecting the damage done to mannans by oxidative radicals.

Structural and biochemical analyses of glycoside hydrolase families 5 and 26 β-(1,4)-mannanases from Podospora anserina reveal differences upon manno-oligosaccharide catalysis

The microbial deconstruction of the plant cell wall is a key biological process that is of increasing importance with the development of a sustainable biofuel industry. The glycoside hydrolase families GH5 (PaMan5A) and GH26 (PaMan26A) endo-β-1,4-mannanases from the coprophilic ascomycete Podospora anserina contribute to the enzymatic degradation of lignocellulosic biomass. In this study, P. anserina mannanases were further subjected to detailed comparative analysis of their substrate specificities, active site organization, and transglycosylation capacity. Although PaMan5A displays a classical mode of action, PaMan26A revealed an atypical hydrolysis pattern with the release of mannotetraose and mannose from mannopentaose resulting from a predominant binding mode involving the -4 subsite. The crystal structures of PaMan5A and PaMan26A were solved at 1.4 and 2.85 A resolution, respectively. Analysis of the PaMan26A structure supported strong interaction with substrate at the -4 subsite mediated by two aromatic residues Trp-244 and Trp-245. The PaMan26A structure appended to its family 35 carbohydrate binding module revealed a short and proline-rich rigid linker that anchored together the catalytic and the binding modules.

CHARCTERISATION OF THE OLIGOSACCHARIDES PRODUCED ON HYDROLYSIS OF GALACTOMANNAN WITH β-D-MANNANASE

Treatment of hot-water-soluble carob galactomannan with β-D-mannanases from A. niger or lucerne seed affords an array of D-galactose-containing β-D-mannosaccharides as well as β-D-manno-biose, -triose, and tetraose (lucerne-seed enzyme only).The D-galactose-containing β-D-mannosaccharides of d.p. 3-9 produced by A. niger β-D-mannanase have been characterised, using enzymic, n.m.r., and chemical techniques, as 61-α-D-galactosyl-β-D-mannobiose, 61-α-D-galactosyl-β-D-mannotriose, 63,64-di-α-D-galactosyl-β-D-mannopentaose (the only heptasaccharide), and 63,64-di-α-D-galactosyl-β-D-mannohexaose, 64,65-di-α-D-galactosyl-β-D-mannohexaose, and 61,63,64-tri-α-D-galactosyl-β-D-mannopentaose (the only octasaccharides).Four nonasaccharides have also been characterised.Penta- and hexa-saccharides were absent.Lucerne-seed β-D-mannanase produced the same branched tri-, tetra- and hepta-saccharides, and also penta- and hexa-saccharides that were characterised as 61-α-D-galactosyl-β-D-mannotetraose, 63-α-D-galactosyl-β-D-mannotetraose, 61,63-di-α-D-galactosyl-β-D-mannotetraose, 63-α-D-galactosyl-β-D-mannopentaose, and 64-α-D-galactosyl-β-D-mannopentaose.None of the oligosaccharides contained a D-galactose stub on the terminal D-mannosyl group nor were they substituted on the second D-mannosyl residue from the reducing terminal.