15548-43-3

Basic information

• Product Name: mannobiose
• Synonyms: Mannopyranose,4-O-b-D-mannopyranosyl- (6CI);Mannopyranose, 4-O-b-D-mannopyranosyl-, D- (8CI); 4-O-b-D-Mannopyranosyl-D-mannopyranose
• CAS NO: 15548-43-3
• Molecular Formula: C₁₂H₂₂O₁₁
• Molecular Weight: 342.29648
• Mol File: 15548-43-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 667.9°Cat760mmHg
• Flash Point: 357.8°C
• Appearance: /
• Density: 1.76g/cm³
• Refractive Index: 1.652
• CAS DataBase Reference: mannobiose(CAS DataBase Reference)
• NIST Chemistry Reference: mannobiose(15548-43-3)
• EPA Substance Registry System: mannobiose(15548-43-3)

Safety Data

• Hazardous Substances Data: 15548-43-3(Hazardous Substances Data)

Usage

Definition

ChEBI: A glycosylmannose that is D-mannopyranose attached to a beta-D-mannopyranosyl group at position 4 via a glycosidic linkage.

InChI:InChI=1/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8+,9+,10-,11u,12+/m1/s1

Upstream product

• 6401-81-6 mannotriose 
• 1263-76-9 O-β-D-mannopyranosyl-(1-4)-O-β-D-mannopyranosyl-(1-4)-O-β-D-mannopyranosyl-(1-4)-D-mannopyranose 

Related news

Regioselective synthesis of mannobiose (cas 15548-43-3) and mannotriose by reverse hydrolysis using a novel 1,6-α-d-mannosidase from Aspergillus phoenicis09/03/2019

A novel 1,6-α-d-mannosidase was produced by Aspergillus phoenicis grown on a commercial manno-oligosaccharide preparation in liquid culture. The enzyme hydrolysed only α-d-Manp-(1→6)-d-Manp and did not act on α-d-Manp-(1→2)-d-Manp, or α-d-Manp-(1→3)-d-Manp. The 1,6-α-d-mannosidase was us...detailed

Short communicationβ 1-4 mannobiose (cas 15548-43-3) enhances Salmonella-killing activity and activates innate immune responses in chicken macrophages08/31/2019

Salmonella spp. is one of the major causes of food-borne illness in humans, and Salmonella enteritidis (SE) infection in commercial poultry is a world-wide problem. Here we have investigated the in vitro immune-modulating effects of β 1-4 mannobiose (MNB), which was previously found to prevent ...detailed

ORIGINAL ARTICLETherapeutic Effects of β1, 4 mannobiose (cas 15548-43-3) in a Balb/c Mouse Model of Intranasally-Induced Pollen Allergy08/29/2019

ABSTRACTBackground: Nutritional prebiotic supplementation represents an attractive approach for interventions of allergy. In this study, the potential therapeutic effect of β-1, 4 mannobiose (MNB) in a murine model of cedar polli- nosis was investigated.Methods: Groups of Balb/c mice were intra...detailed

Relevant articles and documents

Oxidation of mannosyl oligosaccharides by hydroxyl radicals as assessed by electrospray mass spectrometry

The hydroxyl radicals are widely implicated in oxidation of carbohydrates during biological and industrial processes being responsible for their structural modifications and causing functional damage. The identification of intermediate oxidation products is hampered by a lack of reliable sensible methods for their detection. In this study, the oxidation of two models of galactomannans (Man3 and GalMan2) has been studied in reaction with hydroxyl radical generated by Fenton reaction. The oxidation patterns were assessed using preparative ligand-exchange/size-exclusion chromatography (LEX/SEC) coupled with tandem electrospray mass spectrometry (ESI-MS/MS). This allowed the identification of derived oligosaccharides (OS) containing hexuronic, hexonic, pentonic and erythronic acid residues and neutral OS bearing hydroperoxy, hydrated carbonyl moieties and residues from pyranosyl ring cleavage. The depolymerization products have been also detected upon oxidation of oligomers. This study allowed developing a simple, effective 'fingerprinting' protocol for detecting the damage done to mannans by oxidative radicals.

CHARCTERISATION OF THE OLIGOSACCHARIDES PRODUCED ON HYDROLYSIS OF GALACTOMANNAN WITH β-D-MANNANASE

Treatment of hot-water-soluble carob galactomannan with β-D-mannanases from A. niger or lucerne seed affords an array of D-galactose-containing β-D-mannosaccharides as well as β-D-manno-biose, -triose, and tetraose (lucerne-seed enzyme only).The D-galactose-containing β-D-mannosaccharides of d.p. 3-9 produced by A. niger β-D-mannanase have been characterised, using enzymic, n.m.r., and chemical techniques, as 61-α-D-galactosyl-β-D-mannobiose, 61-α-D-galactosyl-β-D-mannotriose, 63,64-di-α-D-galactosyl-β-D-mannopentaose (the only heptasaccharide), and 63,64-di-α-D-galactosyl-β-D-mannohexaose, 64,65-di-α-D-galactosyl-β-D-mannohexaose, and 61,63,64-tri-α-D-galactosyl-β-D-mannopentaose (the only octasaccharides).Four nonasaccharides have also been characterised.Penta- and hexa-saccharides were absent.Lucerne-seed β-D-mannanase produced the same branched tri-, tetra- and hepta-saccharides, and also penta- and hexa-saccharides that were characterised as 61-α-D-galactosyl-β-D-mannotetraose, 63-α-D-galactosyl-β-D-mannotetraose, 61,63-di-α-D-galactosyl-β-D-mannotetraose, 63-α-D-galactosyl-β-D-mannopentaose, and 64-α-D-galactosyl-β-D-mannopentaose.None of the oligosaccharides contained a D-galactose stub on the terminal D-mannosyl group nor were they substituted on the second D-mannosyl residue from the reducing terminal.