155485-71-5

Upstream product

• 155485-70-4 1,2-O-<1-(exo-Cyano)ethylidene>-α-D-fucopyranose 
• 5158-64-5 2,3,4-tri-O-acetyl-D-fucopyranosyl bromide 
• 7404-35-5 1,2,3,4-tetra-O-acetyl-6-deoxy-α-D-galactopyranose 
• 4026-27-1 1,2:3,4-di-O-isopropylidene-α-D-fucopyranose 
• 155485-69-1 3,4-Di-O-acetyl-1,2-O-<1-(exo-cyano)ethylidene>-α-D-fucopyranose 

Downstream Products

• 155485-72-6 4-O-Acetyl-1,2-O-<1-(exo-cyano)ethylidene>-3-O-trityl-α-D-fucopyranose 

Relevant academic research and scientific papers

SYNTHESIS AND POLYCONDENSATION OF GALACTO-CONFIGURATED MONOMERS VIA THE TRITYL-CYANO-ETHYLIDENE-PROCEDURE

4-O-Acetyl-1,2--3-O-trityl-α-D-fucopyranose (13) and methyl 4-O-acetyl-1,2-O--3-O-trityl-α-D-galactopyranuronate (14) were synthesised.Trityl-cyanoethylidene condensation of the monomer 14 gave protected β-D-GalpA-(1->3)-D-GalpA-oligosaccharide derivatives with high stereoselectivity and a degree of polymerisation (d.p.) of eight.In the case of the D-fucose monomer 13, the yield of oligomers is surprisingly low and the d.p. does not exceed seven.This result is in contrast to the d.p. 20 - 60 obtained with other 6-deoxy-sugars, as previously described by Kochetkov and coworkers.