155553-70-1Relevant articles and documents
Evaluation of heteroatom-rich derivatives as antitubercular agents with InhA inhibition properties
Moulkrere, Bachar Rébat,Orena, Beatrice S.,Mori, Giorgia,Saffon-Merceron, Nathalie,Rodriguez, Frédéric,Lherbet, Christian,Belkheiri, Nadji,Amari, Mohamed,Hoffmann, Pascal,Fodili, Mokhtar
, p. 308 - 320 (2018/04/19)
Two series of heterocyclic compounds derived from 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one (DHA) and 2-acetylbutyrolactone have been synthesized and characterized. The compounds were evaluated for their activities against Mycobacterium tuberculosis stra
Structures and Stereochemistries of New Compounds Related to Alternaric Acid
Tabuchi, Hiroyasu,Ichihara, Akitami
, p. 125 - 134 (2007/10/02)
Three alternaric acid-related compounds, viz., 10-deoxyalternaric acid 2, 10-deoxy-6,19-dihydroalternaric acid 3, and 10-deoxy-6,8,9,19-tetrahydroalternaric acid 4, have been isolated from Alternaria solani which is a causal fungus of early blight disease
Metabolites of Lachnellula fuscosanguinea (Rehm). Part 1. The isolation, structure determination, and synthesis of lachnelluloic acid
Ayer, William A.,Villar, J. Daniel Figueroa
, p. 1161 - 1165 (2007/10/02)
The metabolites produced in liquid culture by the fungus Lachnellula fuscosanguinea (Rehm) Dennis have been examined and two antifungal agents, lachnelluloic acid and lachnellulone, have been isolated.The structure of lachnelluloic acid has been established as (-)-4-hydroxy-3-octanoyl-6-pentyl-5,6-dihydro-2-pyrone (1) by chemical and spectroscopic methods.The total synthesis of racemic lachnelluloic acid, starting from 6,8-tridecanedione (6) is reported.Lachnelluloic acid (1) shows strong antifungal activity against Ceratocystis ulmi, the causative agent of Dutch elm disease.