155589-88-1

Basic information

• Product Name: 2-chloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole
• Synonyms: 2-chloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole
• CAS NO: 155589-88-1
• Molecular Weight: 310.995
• Mol File: 155589-88-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole(155589-88-1)
• EPA Substance Registry System: 2-chloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole(155589-88-1)

Safety Data

• Hazardous Substances Data: 155589-88-1(Hazardous Substances Data)

Upstream product

• 151143-59-8 2-nitro-3,4,5-trichloroanisole 
• 54300-74-2 2,3,4-trichloro-6-methoxyaniline 
• 54135-82-9 3,4,5-trichloroanisole 
• 33719-74-3 3,5-dichloroanisole 

Downstream Products

• 155589-90-5 2,5-dichloro-1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole 

Relevant articles and documents

Total synthesis of (+)- and (-)-neopyrrolomycins, chlorinated phenylpyrrole antibiotics

The first total synthesis of (+)- and (-)-neopyrrolomycins (11a and 11b) is detailed based on regioselective chlorinations of 3,5-dichloroanisole (2) and 1-(2,3,4-trichloro-6-methoxyphenyl)-1H-pyrrole-2-carboxylic acid (8) with isocyanuric trichloride, followed by optical resolution of racemic neopyrrolomycin (11) with N-(p-tolylsulfonyl)-L-phenylalanyl chloride. Several analogs (21-25) have been prepared from the intermediates, and the structure-activity relationships are also discussed.