155601-71-1

Basic information

• Product Name: TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE
• Synonyms: TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE;tert-Butyl 6-fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate 97%;tert-Butyl6-fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate97%;tert-Butyl 6-fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate ,95%;3-(tert-Butoxycarbonyl)-6-fluoro-1H-pyrazolo[3,4-b]pyridine;tert-butyl 6-fluoro-2H-pyrazolo[3,4-b]pyridine-3-carboxylate;1H-Pyrazolo[3,4-b]pyridine-3-carboxylicacid, 6-fluoro-, 1,1-dimethylethyl ester
• CAS NO: 155601-71-1
• Molecular Formula: C₁₁H₁₂FN₃O₂
• Molecular Weight: 237.23
• Mol File: 155601-71-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 165.5-168.5
• Boiling Point: 378 °C at 760 mmHg
• Flash Point: 182.4 °C
• Appearance: /
• Density: 1.318 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE(155601-71-1)
• EPA Substance Registry System: TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE(155601-71-1)

Safety Data

• Hazard Codes: Harmful:
• Hazardous Substances Data: 155601-71-1(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 6-Fluoro-1H-Pyrazolo[3,4-b]pyridine-3-carboxylate, also known as CAS Number 241479-67-4, is a chemical compound belonging to the category of fluorinated compounds. It is commonly used in the synthesis and manufacture of other chemicals, particularly pharmaceuticals. TERT-BUTYL 6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXYLATE's molecular formula is C12H14FN3O2 and it is noted for its physical properties which include a molecular weight of 249.25, density of 1.2 g/cm3, and boiling point of 370.8°Cat 760 mmHg. It is a white, crystalline powder that has a high degree of stability and a very low level of toxicity. Routinely stored at room temperature, it is characterized by its high level of reactivity with various substances. Further precautions are necessary while handling this chemical due to its potential for flammability.

InChI:InChI=1/C11H12FN3O2/c1-11(2,3)17-10(16)8-6-4-5-7(12)13-9(6)15-14-8/h4-5H,1-3H3,(H,13,14,15)

Upstream product

• 7732-18-5 water 
• 155601-70-0 2,6-Difluoropyridine-3-(α-oxo)acetic acid, t-butyl ester 
• 75716-83-5 tert-butyl α-oxo-1H-imidazole-1-acetate 
• 1513-65-1 2,6-difluoro pyridine 

Downstream Products

• 155601-83-5 6-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 
• 932702-22-2 tert-butyl 6-phenyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylate 
• 1034474-34-4 3-chloro-5-{[5-chloro-1-({1-(4-methoxybenzyl)-6-[(4-methoxybenzyl)amino]-1H-pyrazolo[3,4-b]pyridin-3-yl}methyl)-1H-indazol-4-yl]oxy}benzonitrile 
• 1034474-25-3 3-(chloromethyl)-N,1-bis(methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-6-amine 
• 1034474-28-6 {1-(4-methoxybenzyl)-6-[(4-methoxybenzyl)amino]-1H-pyrazolo[3,4-b]pyridin-3-yl}methanol 
• 1345336-22-2 3-({1-[(6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methyl]-5-chloro-1H-1,2,3-benzotriazol-4-yl}oxy)-5-chlorobenzonitrile 
• 1345337-40-7 3-{[5-chloro-4-(3-chloro-5-cyanophenoxy)-1H-1,2,3-benzotriazol-1-yl]methyl}-1H-pyrazolo[3,4-b]pyridin-6-aminium chloride 
• 1345337-21-4 3-(chloromethyl)-N,2-bis(4-methoxybenzyl)-2H-pyrazolo[3,4-b]pyridin-6-amine 
• 1345337-24-7 3-chloro-5-{[5-chloro-1-({2-(4-methoxybenzyl)-6-[(4-methoxybenzyl)amino]-2H-pyrazolo[3,4-b]pyridin-3-yl}methyl)-1H-1,2,3-benzotriazol-4-yl]oxy}benzonitrile 
• 1034474-35-5 3-({1-[(6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methyl]-5-chloro-1H-indazol-4-yl}oxy)-5-chlorobenzonitrile 
• 1034474-20-8 3-{[5-chloro-4-(3-chloro-5-cyanophenoxy)-1H-indazol-1-yl]methyl}-1H-pyrazolo[3,4-b]pyridin-6-aminium chloride 
• 1345337-17-8 3-chloro-5-{[5-chloro-2-({1-(4-methoxybenzyl)-6-[(4-methoxybenzyl)amino]-1H-pyrazolo[3,4-b]pyridin-3-yl}methyl)-2H-indazol-4-yl]oxy}benzonitrile 
• 1034474-27-5 tert-butyl 1-(4-methoxybenzyl)-6-[(4-methoxybenzyl)amino]-1H-pyrazolo[3,4-b]pyridine-3-carboxylate 
• 1034474-26-4 tert-butyl 6-fluoro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate 

Relevant articles and documents

Synthesis of some piperazinylpyrazolo[3,4-b]pyridines as selective serotonin re-uptake inhibitors

A number of 3-substituted 6-piperazinylpyrazolo[3,4-b]pyridines were synthesized from 2,6-difluoropyridine by directed ortho metallation and sequential intra- and intermolecular displacement of fluorine. Three derivatives with a cyano group in the 3-position showed activity as selective serotonin re-uptake inhibitors.