155660-91-6Relevant articles and documents
Synthesis of derivatives of potent antitumor bistramides D and A leading to the first crystal structure of natural bistramide D
Bauder, Claude,Biard, Jean-Franois,Solladie, Guy
, p. 1860 - 1862 (2006)
The synthesis of derivatives of potent antitumor bistramides D and A, which led to the first crystal structure of natural bistramide D, was discussed. The absolute configuration of a chemical derivative of bistramide D by radiocrystallographic analysis starting from the natural material was analyzed. The structural assignment of bistramide D was resolved using an alternative strategic scheme, based on studies of derivatives of natural bistramide. The research was focused on the derivatives of the natural bistramide because of the structural complexity of bistramide D and its great number of possible stereoisomer.