1556785-71-7

Upstream product

• 1556785-54-6 bis-1,2-(4-bromo-5-t-butylamido-1H-pyrazol-1-yl)ethane 
• 1609-86-5 Tert-butyl isocyanate 
• 116476-96-1 bis-1,2-(4-bromo-1H-pyrazol-1-yl)ethane 

Relevant academic research and scientific papers

Formation of dilithiated bis-(1H-pyrazol-1-yl)alkanes and their application in the synthesis of diboronic acids

Bis-(1H-pyrazol-1-yl)alkanes were deprotonated at the pyrazole 5-positions on treatment with LDA in THF at low temperature. These dianions reacted with tert-butylisocyanate as the electrophile to install a tert-butylamide group at the pyrazole 5-position.