15568-86-2

Basic information

• Product Name: 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione
• Synonyms: 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione;1,3-Dioxane-4,6-dione, 5-(ethoxyMethylene)-2,2-diMethyl-
• CAS NO: 15568-86-2
• Molecular Formula: C₉H₁₂O₅
• Molecular Weight: 200.18858
• Mol File: 15568-86-2.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione(15568-86-2)
• EPA Substance Registry System: 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione(15568-86-2)

Safety Data

• Hazardous Substances Data: 15568-86-2(Hazardous Substances Data)

Usage

General Description

5-(ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione is a chemical compound that is used in the field of organic chemistry. It is a cyclic compound with a dioxane ring structure and contains a methylene group attached to an ethoxy group. 5-(ethoxyMethylene)-2,2-diMethyl-1,3-dioxane-4,6-dione is commonly used as a reagent in organic synthesis, particularly in the formation of heterocyclic compounds. It is also used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is known for its unique reactivity and is used as a building block for the synthesis of more complex organic molecules. Overall, 5-(ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione plays an important role in the advancement of organic chemistry and the development of various chemical products.

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 143618-90-0 5-<<-2-<1-(benzenesulfonyl)indolyl>>methylidene>-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 155248-00-3 N-{3-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-2-methyl-phenyl}-acetamide 
• 89044-58-6 2,2-dimethyl-5-<1-(2-methylpiperidino)methylene>-1,3-dioxane-4,6-dione 
• 25063-44-9 2,2-Dimethyl-5-(p-tolylamino-methylene)-[1,3]dioxane-4,6-dione 
• 25063-47-2 2,2-dimethyl-5-(((2-nitrophenyl)amino)methylene)-1,3-dioxane-4,6-dione 
• 25253-09-2 5-{[(2-methylphenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 750647-77-9 5-[(2,3-diphenylquinoxalin-5-ylamino)methylene]-2,2-dimethyl-[1,3]-dioxane-4,6-dione 
• 219763-81-2 4-[(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-benzonitrile 
• 155953-31-4 5-{2-[3-Ethyl-3H-benzothiazol-(2E)-ylidene]-ethylidene}-2,2-dimethyl-[1,3]dioxane-4,6-dione 
• 118060-61-0 5-(N-N-dibenzyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 15568-93-1 5-(N-methyl-N-phenyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 118060-63-2 5-(N-benzyl-N-methyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 25063-81-4 5-(N-ethyl-N-phenyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 95079-99-5 5-<2-(<2,2,6,6-2H4>cyclohexyl)-2-azaethylidene>-2,2-dimethyl-1,3-dioxane-4,6-dione 

Relevant articles and documents

Application of Pd-Catalyzed Cross-Coupling Reactions in the Synthesis of 5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles that Inhibit ALK5 Kinase

C-H activation of position 3 of a substituted pyrazole ring catalyzed by palladium(II) was straightforward and convenient for arylated or heteroarylated 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles. Moreover, we introduced simple protection of the nitrogen in the pyridin-2-yl directing group, which otherwise does not allow a cross-coupling reaction, by transformation to the N-oxide. Selected final products were reasonably selective ALK5 kinase inhibitors.

Development of novel quinoline-based sulfonamides as selective cancer-associated carbonic anhydrase isoform ix inhibitors

A new series of quinoline-based benzenesulfonamides (QBS) were developed as potential carbonic anhydrase inhibitors (CAIs). The target QBS CAIs is based on the 4-anilinoquinoline scaffold where the primary sulphonamide functionality was grafted at C4 of t

Vascular endothelial growth factor receptor inhibitor and preparation method and application thereof

The invention provides a vascular endothelial growth factor receptor inhibitor and a preparation method and application thereof, and relates to a quinoline or quinazoline derivative with a structure as shown in a formula (I), a pharmaceutical composition containing a compound as shown in the formula (I) and application of the compound in preparation of drugs for preventing or treating angiogenesis-related diseases, in particular to prevention or treatment of tumors related to protein tyrosine kinase. Each substituent in the formula (I) is the same as the definition in the specification.