1557154-80-9Relevant articles and documents
Development of Large-Scale Synthesis using a Palladium-Catalyzed Cross-Coupling Reaction for an Isoquinolone Derivative as a Potent DPP-4 Inhibitor
Sera, Misayo,Yamashita, Makoto,Ono, Yuujirou,Tabata, Takashi,Muto, Eigo,Ouchi, Takashi,Tawada, Hiroyuki
, p. 446 - 453 (2014/04/17)
An efficient large-scale synthesis of a novel DPP-4 inhibitor 1, an isoquinolone derivative bearing an aminomethyl group at the 3-position and carbamoylmethoxy group at the 6-position, is described. We have developed an effective and convenient synthetic