155721-03-2Relevant articles and documents
Synthesis of panaxytriol and its stereoisomers as potential antitumor drugs
Mao, Jianyou,Zhong, Jiangchun,Wang, Bo,Jin, Jing,Li, Shuoning,Gao, Zidong,Yang, Hanze,Bian, Qinghua
, p. 330 - 337 (2016)
An efficient synthesis of panaxytriol and its seven stereoisomers was achieved, and four unnatural diastereomers of 2a were prepared. The key steps involved the opening of vicinal hydroxy epoxides, the stereospecific opening of the epoxides with perchlori
Ring opening of 2,3-epoxy 1-tosylates to halohydrins and subsequent elaboration to asymmetrical alcohols
Federici,Federici, Chiara,Righi,Righi, Giuliana,Rossi,Rossi, Leucio,Bonini,Bonini, Carlo,Chiummiento,Chiummiento, Lucia,Funicello,Funicello, Maria
, p. 797 - 800 (2007/10/02)
2,3-epoxy alcohols-1-tosylates are regio and chemoselectively opened to the corresponding 3-halohydrins (I, Br, Cl): the reduction of the iodohydrins to the monoprotected diols and subsequent standard coupling of the tosyl group leads to a straightforward synthesis of optically active naturally occurring pheromones