1557268-58-2

Basic information

• Product Name: N-(3-fluoro-4- (4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine
• Synonyms: N-(3-fluoro-4- (4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine
• CAS NO: 1557268-58-2
• Molecular Weight: 593.733
• Mol File: 1557268-58-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-fluoro-4- (4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-fluoro-4- (4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine(1557268-58-2)
• EPA Substance Registry System: N-(3-fluoro-4- (4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine(1557268-58-2)

Safety Data

• Hazardous Substances Data: 1557268-58-2(Hazardous Substances Data)

Upstream product

• 90213-66-4 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 
• 442847-52-1 2,4-dichloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3 -d]pyrimidine 
• 221198-99-8 1-(2-fluoro-4-aminophenyl)-4-methylpiperazine 
• 1557268-35-5 2-chloro-4-(3-nitrophenoxy)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-D]pyrimidine 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 

Downstream Products

• 1557268-61-7 4-(3-aminophenoxy)-N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-7-((2-(trimethylsilyl)ethyloxy)methyl)-7H-pyrrolo[2,3-D]pyrimidin-2-amine 

Relevant articles and documents

Novel synthesis route and maleate dihydrate of avitinib

The invention discloses a novel synthesis route of avitinib. 2-chlorine-4-(3-nitryl phenoxy)-7-hydrogen-(pyrrolo[2,3-d] pyrimidine)-1-methyl tert-butyrate is adopted as an initial raw material, the reaction route is short, the total yield is high, a prote