155727-47-2Relevant academic research and scientific papers
A convenient synthesis of 6-hydroxyharman
Rocca, Patrick,Marsais, Francis,Godard, Alain,Queguiner, Guy
, p. 2003 - 2004 (1994)
A three-step synthesis of 6-hydroxyharman and 6-hydroxynorharman from benzene and pyridine blocks is described. The preparation of the two α-substituted β-carbolines is based on a new synthetic methodology which involves reactions such as Directed Ortho M
Carbolines. Part VII. Anisidines, convenient tools to synthesize hydroxy-β-carbolines
Rocca,Marsais,Godard,Queguiner,Adams,Alo
, p. 1171 - 1175 (2007/10/02)
The paper describes a convenient synthesis of hydroxy-β-carbolines from commercial anisidines based on key steps such as metalation, cross-coupling and cyclization. The first total synthesis of a major cytotoxic constituent of a marine bryozoan is also re
