Ensaculin is a potent and selective inhibitor of monoamine oxidase-B (MAO-B) with significant neuroprotective effects, making it a promising candidate for the treatment of neurodegenerative diseases such as Parkinson's disease. Its high selectivity for MAO-B over MAO-A, along with its antioxidant and anti-inflammatory properties, further support its potential as a therapeutic agent.
155773-59-4
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Basic information
- Product Name: Ensaculin
- Synonyms: Ensaculin;Anseculin
- CAS NO:155773-59-4
- Molecular Formula: C26H32N2O5
- Molecular Weight: 452.54268
- EINECS: N/A
- Product Categories: N/A
- Mol File: 155773-59-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 632°Cat760mmHg
- Flash Point: 336°C
- Appearance: /
- Density: 1.169g/cm3
- Vapor Pressure: 7.01E-16mmHg at 25°C
- Refractive Index: 1.567
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 7.35±0.10(Predicted)
- CAS DataBase Reference: Ensaculin(CAS DataBase Reference)
- NIST Chemistry Reference: Ensaculin(155773-59-4)
- EPA Substance Registry System: Ensaculin(155773-59-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 155773-59-4(Hazardous Substances Data)
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155773-59-4 Usage
Uses
Used in Neurodegenerative Disease Treatment:Ensaculin is used as a neuroprotective agent for the treatment of neurodegenerative diseases, particularly Parkinson's disease. It enhances dopaminergic transmission in the brain, providing significant neuroprotective effects and potentially slowing the progression of the disease.
Used in Drug Development:
Ensaculin is used as a candidate for drug development due to its high selectivity for MAO-B, which could reduce the risk of side effects associated with non-selective MAO inhibitors. Its antioxidant and anti-inflammatory properties also contribute to its potential as a therapeutic agent for neurodegenerative disorders.
Despite facing some challenges in development, Ensaculin remains an interesting candidate for the treatment of neurodegenerative diseases, offering a promising avenue for further research and development in this field.
Check Digit Verification of cas no
The CAS Registry Mumber 155773-59-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,7,7 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.Calculate Digit Verification of CAS Registry Number 155773-59:
(8*1)+(7*5)+(6*5)+(5*7)+(4*7)+(3*3)+(2*5)+(1*9)=164
164 % 10 = 4
So 155773-59-4 is a valid CAS Registry Number.
InChI:InChI=1/C26H32N2O5/c1-18-19(2)26(29)33-23-17-24(31-4)25(16-20(18)23)32-15-7-10-27-11-13-28(14-12-27)21-8-5-6-9-22(21)30-3/h5-6,8-9,16-17H,7,10-15H2,1-4H3
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Ensaculin
