155779-79-6

Upstream product

• 90719-29-2 (4S)-3-((E)-2-butenoyl)-4-(1-methylethyl)-2-oxazolidinone 
• 98-80-6 phenylboronic acid 
• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 591-51-5 phenyllithium 

Downstream Products

• 155779-81-0 (4S)-3-<(2S,3R)-1-oxo-2-<<(2-phenylethyl)thio>methyl>-3-phenylbutyl>-4-(1-methylethyl)-2-oxazolidinone 

Relevant academic research and scientific papers

Palladium-Catalyzed Diastereoselective Synthesis of 3-Arylbutanoic Acid Derivatives

The first palladium-catalyzed diastereoselective conjugate addition of arylboronic acids to chiral imides is reported. The catalytic system employing 4-tert-butyloxazolidin-2-one as the chiral auxiliary in a mixed solvent system of MeOH/H2O (1:3) under an air atmosphere provides the optically active 3-arylbutanoic acid derivatives in excellent yields with high diastereoselectivity.

Asymmetric conjugate additions of TMSI promoted monoorganocuprate reagents, Li[RCuI], to various N-enoyl oxazolidinones

Diastereoselective conjugate additions to different α,β-unsaturated N-acyl oxazolidinones using various monoorganocuprate reagents, Li[RCuI], are described. The TMSI activated conjugate addition reactions provided high yields (80-98%) and reversed major d