15579-44-9

Usage

Uses

Used in Pharmaceutical Industry:
Imipramine is used as a therapeutic agent for the treatment of depression and panic disorders. It functions by increasing the levels of serotonin and norepinephrine, key neurotransmitters that contribute to mood regulation and anxiety reduction, thereby improving the overall mental well-being of patients.
Used in Research and Development:
In the scientific community, Imipramine serves as a valuable research tool for studying the mechanisms of mood disorders and the effects of tricyclic antidepressants on neurotransmitter systems. This helps in the development of new and more effective treatments for various mental health conditions.
Used in Clinical Settings:
Imipramine is utilized in clinical practice as a prescribed medication for patients diagnosed with depression or panic disorders. Its administration is carefully monitored by healthcare professionals to ensure optimal therapeutic outcomes and minimize potential side effects.

Upstream product

• 5211-86-9 N-(dimethoxymethyl)piperidine 
• 106-47-8 4-chloro-aniline 

Relevant academic research and scientific papers

Amidines. Part 31. pKa Values of N1,N1-Dialkyl-N2-phenylformamidines in Water-Ethanol Solutions

The pKa values of three series (30 compounds in all) of N1,N1-dialkyl-N2-phenylformamidines (XC6H4N=CHNRR) have been measured in water-ethanol mixtures.The obtained pKa values of the amidines have been correlated with Hammett-type substituent constants and the pKa values of the corresponding primary amines determined in the same solvent.The applicability of various ? values is discussed and it is shown that, in each case, for substituents on the phenyl ring at the amino nitrogen atom ?0 values should be used.It is found that the slopes of regression lines for correlations with Hammett-type constants depend on the substituents at the amino nitrogen atom, as well as on the solvent.

Amidines. Part 20. Rate of Reaction of N,N-Dialkylformamide Acetals with Substituted Anilines

Rate of reaction of seven N,N-dialkylformamide acetals R2N-CH(OR2)2 with a series of anilines substituted on the phenyl ring have been measured in benzene, methanol, chloroform, and tetrahydrofuran by use of a g.l.c. method.In each case studied reaction is irreversible and obeys a second-order kinetic equation.Reaction rates correlate with Hammett ? constants for substituents on the phenyl ring of the aniline molecule.On the basis of the kinetic data, the mechanism of reaction is discussed.