155794-57-3

Basic information

• Product Name: 2-Propanone, 1-fluoro-1-(2-pyridinyl)-
• Synonyms: 2-Propanone, 1-fluoro-1-(2-pyridinyl)-
• CAS NO: 155794-57-3
• Molecular Formula: C8H8FNO
• Molecular Weight: 153.15
• Mol File: 155794-57-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 218.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.131±0.06 g/cm3(Predicted)
• PKA: 2.22±0.19(Predicted)
• CAS DataBase Reference: 2-Propanone, 1-fluoro-1-(2-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1-fluoro-1-(2-pyridinyl)-(155794-57-3)
• EPA Substance Registry System: 2-Propanone, 1-fluoro-1-(2-pyridinyl)-(155794-57-3)

Safety Data

• Hazardous Substances Data: 155794-57-3(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 139032-23-8 1-isocyano-4-(trifluoromethyl)benzene 
• 6302-02-9 2-acetonylpyridine 
• 2684-62-0 diazoacetone 
• 107264-09-5 1-fluoro-pyridinium tetrafluoroborate 

Relevant articles and documents

Asymmetric α-Functionalization of 2-Alkyl Azaarenes: Synthesis of Tertiary Fluorides Having Vicinal Stereogenic Centers

An enantioselective approach for synthesizing fluorinated azaarenes containing vicinal quaternary–tertiary stereocenters is summarized. The chiral copper(I)–phosphine complex binds with the azaarenes followed by Michael addition to unsaturated acyl imidazoles, resulting in α-functionalized products with an excellent level of enantioselectivities (up to 99%), diastereoselectivities (>20:1), and yields (up to 97%). Furthermore, post-functionalization of the acyl imidazole part has also been demonstrated.

Reaction of N-fluoropyridinium fluoride with isonitriles and diazo compounds: A one-pot synthesis of (pyridin-2-yl)-1H-1,2,3-triazoles

Reaction of N-fluoropyridinium fluoride generated in situ with a series of isonitriles and diazo compounds led to the formation of the corresponding (pyridine-2-yl)-1H-1,2,3-triazoles in good yields (37-59%). Best outcome was consistently achieved with bo