1558003-53-4

Upstream product

• 1558003-47-6 (3R)-methyl 3-hydroxy-7-(4-methoxybenzyloxy)-2,2-dimethylhept-4-ynoate 
• 13865-20-8 methyl 2,2-dimethyl-3-oxopropanoate 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 1558003-51-2 (3R,4E)-methyl 3-hydroxy-7-(4-methoxybenzyloxy)-2,2,4-trimethylhept-4-enoate 
• 14002-80-3 Methyl 2,2-dimethyl-3-hydroxypropionate 
• 1558003-50-1 (3S,4Z)-methyl 3-hydroxy-4-iodo-7-(4-methoxybenzyloxy)-2,2-dimethylhept-4-enoate 
• 1558003-48-7 (3S,4Z)-methyl 3-hydroxy-7-(4-methoxybenzyloxy)-2,2-dimethyl-4-(triphenylstannyl)hept-4-enoate 

Relevant academic research and scientific papers

Asymmetric total synthesis of (+)-inthomycin C via O-directed free radical alkyne hydrostannation with Ph3SnH and catalytic Et3B: Reinstatement of the zeeck-taylor (3 R)-Structure for (+)-Inthomycin C

A new pathway to (+)-inthomycin C is reported that exploits an O-directed free radical hydrostannation reaction on (-)-12 and a Stille cross-coupling as key steps. Significantly, the latter process was effected on 19 where a gauche-pentane repulsive inter