1558007-30-9Relevant academic research and scientific papers
Synthesis and spectroscopic characterization of indomethacin-Cd(II), Ce(III), and Th(IV) complexes: IR, 1H NMR, thermal, and biological studies
Refat, Moamen S.,Mohamed, Gehad G.,Ibrahim, Mohamed Y. S.,Killa, Hamada M. A.,Fetooh, Hammad
, p. 2479 - 2487 (2013)
Solid complexes have been prepared and characterized by IR, UV-Vis, elemental analysis, and 1H NMR. Indomethacin forms complexes with Cd(II), Ce(III), and Th(IV) ions in molar ratios (ligand: metal) (2: 1), (3: 1), and (4: 1), respectively. The IR spectra of the complexes suggest that the Indomethacin behaves as a monobasic monodentate ligand coordinated to the metal ions via the deprotonated carboxylate group. Prepared complexes exhibit higher antimicrobial activity against several microorganisms, compared to free ligand.
