155801-51-7

Basic information

• Product Name: 5,7-dimethoxy-4-methyl-2-oxo-2H-chromen-6-yl acetate
• Synonyms: 5,7-dimethoxy-4-methyl-2-oxo-2H-chromen-6-yl acetate
• CAS NO: 155801-51-7
• Molecular Formula: C14H14O6
• Molecular Weight: 278.25736
• Mol File: 155801-51-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,7-dimethoxy-4-methyl-2-oxo-2H-chromen-6-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-dimethoxy-4-methyl-2-oxo-2H-chromen-6-yl acetate(155801-51-7)
• EPA Substance Registry System: 5,7-dimethoxy-4-methyl-2-oxo-2H-chromen-6-yl acetate(155801-51-7)

Safety Data

• Hazardous Substances Data: 155801-51-7(Hazardous Substances Data)

Upstream product

• 6093-80-7 5,7-dimethoxy-4-methylcoumarin 
• 500-99-2 3,5-dimethoxyphenol 
• 107055-08-3 6-hydroxy-5,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one 
• 108-24-7 acetic anhydride 
• 15233-65-5 2,6-dimethoxy-1,4-hydroquinone 

Relevant articles and documents

Anti-invasive activity of 3,7-dimethoxyflavone in vitro

Invasion of MCF-7/6 human mammary carcinoma cells into embryonic chick heart fragments was studied in organ culture during 8 days. The effect of 31 polyphenolic compounds, belonging to the flavonoids, chalcones, or coumarins, was tested in this assay for invasion. The anti-invasive activity of 3,7- dimethoxyflavone was found at concentrations ranging from 1 to 100 μM. At these anti-invasive concentrations, no cytotoxic effects could be detected: the anti-invasive effect was reversible upon omission of the molecule from the medium, and treatment of MCF-7/6 cells or heart fragments did not affect subsequent outgrowth from explants on tissue culture plastic. The molecule did not inhibit growth of MCF-7/6 cell aggregates nor of heart fragments kept in suspension culture. The action mechanism of 3,7-dimethoxyflavone is the subject of our ongoing research.