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155861-24-8

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155861-24-8 Usage

General Description

Isopropyl 4-(3-Aminophenyl)-1,4-dihydro-5-(2-Methoxyethoxycarbonyl)-2,6-dimethylpyridine-3-carboxylate is a chemical compound with a complex structure. It contains isopropyl, aminophenyl, dihydro, methoxyethoxycarbonyl, dimethylpyridine, and carboxylate functional groups. Isopropyl 4-(3-AMinophenyl)-1,4-dihydro-5-(2-Methoxyethoxycarbonyl)-2,6-diMethylpyridine-3-carboxylate is likely to have pharmaceutical or medicinal applications due to the presence of the aminophenyl group, which is often found in drugs targeting the central nervous system and other therapeutic areas. Additionally, the presence of the dihydro and carboxylate groups suggests potential biological activity, making this compound an interesting candidate for further research and development in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 155861-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,8,6 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 155861-24:
(8*1)+(7*5)+(6*5)+(5*8)+(4*6)+(3*1)+(2*2)+(1*4)=148
148 % 10 = 8
So 155861-24-8 is a valid CAS Registry Number.

155861-24-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name isopropyl 2-methoxyethyl 4-(3-aminophenyl)-1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names Isopropyl 4-(3-Aminophenyl)-1,4-dihydro-5-(2-methoxyethoxycarbonyl)-2,6-dimethylpyridine-3-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155861-24-8 SDS

155861-24-8Downstream Products

155861-24-8Relevant articles and documents

Substrate selectivity of human aldehyde oxidase 1 in reduction of nitroaromatic drugs

Ogiso, Takuo,Fukami, Tatsuki,Mishiro, Kenji,Konishi, Keigo,Jones, Jeffrey P.,Nakajima, Miki

, p. 85 - 92 (2018)

Human aldehyde oxidase 1 (AOX1) catalyzes the oxidation of various drugs and endogenous compounds. Recently, we found that AOX1 catalyzed the reduction of drugs such as nitrazepam and dantrolene. In this study, we aimed to clarify the substrate selectivit

Simple RuCl3-catalyzed N-Methylation of Amines and Transfer Hydrogenation of Nitroarenes using Methanol

Sarki, Naina,Goyal, Vishakha,Tyagi, Nitin Kumar,Puttaswamy,Narani, Anand,Ray, Anjan,Natte, Kishore

, p. 1722 - 1729 (2021/04/19)

Methanol is a potential hydrogen source and C1 synthon, which finds interesting applications in both chemical synthesis and energy technologies. The effective utilization of this simple alcohol in organic synthesis is of central importance and attracts scientific interest. Herein, we report a clean and cost-competitive method with the use of methanol as both C1 synthon and H2 source for selective N-methylation of amines by employing relatively cheap RuCl3.xH2O as a ligand-free catalyst. This readily available catalyst tolerates various amines comprising electron-deficient and electron-donating groups and allows them to transform into corresponding N-methylated products in moderate to excellent yields. In addition, few marketed pharmaceutical agents (e. g., venlafaxine and imipramine) were also successfully synthesized via late-stage functionalization from readily available feedstock chemicals, highlighting synthetic value of this advanced N-methylation reaction. Using this platform, we also attempted tandem reactions with selected nitroarenes to convert them into corresponding N-methylated amines using MeOH under H2-free conditions including transfer hydrogenation of nitroarenes-to-anilines and prepared drug molecules (e. g., benzocaine and butamben) as well as key pharmaceutical intermediates. We further enable one-shot selective and green syntheses of 1-methylbenzimidazole using ortho-phenylenediamine (OPDA) and methanol as coupling partners.

FE NANOPARTICLES WITH PPM CONTENTS OF PD, CU AND/OR NI, REACTIONS IN WATER CATALYZED BY THEM

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Paragraph 0069, (2017/07/14)

The present application discloses a nanoparticle composition prepared from a mixture comprising: a) a transition metal salt; b) an iron salt; and c) a reducing agent; and methods for the use of such compositions, including the reduction of an organic compound comprising a nitro group to form an organic compound comprising an amine group, the Cu-catalyzed cyclization of an azide and an alkyne (click chemistry) and cross coupling reactions, notably Suzuki-Miyaura reactions. The transition metal salts are in particular Pd, Cu and Ni salts, the content of these metals being typically in the ppm range based on the major constituent Fe in the final products.

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