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2-(4-Isothiocyanatophenoxy)ethyl Tosylat, also known as ITP-Tosylat, is a heterobifunctional linker with specific applications in chemical synthesis and molecular biology. It is characterized by its ability to quaternize pyridyl-nitrogen, which allows for the introduction of amine or thiol reactive groups. This unique property makes ITP-Tosylat a valuable synthetic building block in various fields.

155863-33-5

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155863-33-5 Usage

Uses

Used in Chemical Synthesis:
ITP-Tosylat is used as a heterobifunctional linker for the quaternisation of pyridyl-nitrogen in order to introduce an amine or thiol reactive group. This application is crucial in the synthesis of various chemical compounds, as it enables the formation of new bonds and the creation of complex molecular structures.
Used in Molecular Biology:
In the field of molecular biology, ITP-Tosylat serves as a synthetic building block for the preparation of fluorescent labels. These labels are essential for various research applications, including the study of protein-protein interactions, cellular localization, and the tracking of biomolecules within living cells. The introduction of amine or thiol reactive groups through ITP-Tosylat allows for the attachment of fluorescent dyes to target molecules, enabling their detection and analysis under various experimental conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 155863-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,8,6 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 155863-33:
(8*1)+(7*5)+(6*5)+(5*8)+(4*6)+(3*3)+(2*3)+(1*3)=155
155 % 10 = 5
So 155863-33-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO4S2/c1-13-2-8-16(9-3-13)23(18,19)21-11-10-20-15-6-4-14(5-7-15)17-12-22/h2-9H,10-11H2,1H3

155863-33-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (02977)  2-(4-Isothiocyanatophenoxy)ethyltosylate  ≥98.0% (TLC)

  • 155863-33-5

  • 02977-1G-F

  • 3,923.01CNY

  • Detail

155863-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-isothiocyanatophenoxy)ethyl 4-methylbenzenesulfonate

1.2 Other means of identification

Product number -
Other names 2-(4-Isothiocyanatophenoxy)ethyl tosylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155863-33-5 SDS

155863-33-5Downstream Products

155863-33-5Relevant academic research and scientific papers

Syntheses of Reactive Fluorescent Stains Derived from 5(2)-Aryl-2(5)-(4-pyridyl)oxazoles and Bifunctionally Reactive Linkers

Litak, Peter T.,Kauffman, Joel M.

, p. 457 - 480 (2007/10/02)

Several bifunctionally reactive linkers containing halide or sulfonate ester groups were prepared.The linkers were used to quaternize 5-(4-methoxyphenyl)-2-(4-pyridyl)oxazole and 2-(6-chromanyl)-5-(4-pyridyl)oxazole to produce fluorescent stains that contained a reactive group such as an isothiocyanate, an N-hydroxysuccinimidyl ester, a maleimide, or an oxirane.The stains were derivatized with either 1-propyl-amine, 1-propanethiol, or piperidine, as appropriate, to help in characteriazation.The stains may serve as more photostable alternatives to fluoresceins or coumarins.

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