155873-94-2Relevant academic research and scientific papers
Practical asymmetric version of the intermolecular Pauson-Khand reaction
Bernardes, Vania,Verdaguer, Xavier,Kardos, Nathalie,Riera, Antoni,Moyano, Albert,Pericas, Miquel A.,Greene, Andrew E.
, p. 575 - 578 (1994)
The first practical asymmetric version of the intermolecular Pauson-Khand reaction has been developed based on novel chiral (non-racemic) alkoxy acetylene dicobalt hexacarbonyl complexes. The major adduct from (1R,2S)-2-phenylcyclohexyloxyethyne and norbornadiene, isolated in 58% yield, is shown to be useful for obtaining chiral 4-substituted 2-cyclopentenones.
