155883-35-5

Upstream product

• 155883-36-6 3-hydroxy-2-phenyl-4H-pyrazolo<1,5-a>indole 
• 141235-77-0 (3SR,3aSR)-3-hydroxy-2-phenyl-3a,4-dihydro-3H-pyrazolo<1,5-a>indole 

Downstream Products

• 155913-88-5 3-hydroxy-3-methyl-2-phenyl-3H-pyrazolo<1,5-a>indole 
• 155883-41-3 3-<4-(3-hydroxy-2-phenyl-4H-pyrazolo<1,5-a>indolyl)>pent-2,4-dione 
• 155883-42-4 diethyl 2-<4-(3-hydroxy-2-phenyl-4H-pyrazolo<1,5-a>indolyl)>malonate 
• 155883-37-7 3-acetoxy-2-phenyl-4H-pyrazolo<1,5-a>indole 
• 155883-47-9 2-<4-(3-oxo-2-phenyl-3H-pyrazolo<1,5-a>indolyl)>cyclohexanone 
• 155913-87-4 3-acetoxy-2-phenyl-3H-pyrazolo<1,5-a>indole 
• 155913-96-5 3-hydroxy-2-phenyl-<3-²H₁>-3H-pyrazolo<1,5-a>indole 
• 155883-36-6 3-hydroxy-2-phenyl-4H-pyrazolo<1,5-a>indole 

Relevant academic research and scientific papers

Preparation and reaction of 3-oxo-3H-pyrazolo[1,5-a]indole derivatives

An alternative method to prepare 3-oxo-2-phenyl-3H-pyrazolo[1,5-a]indole starting from indoline-2-carboxylic acid was explored. The reaction with nucleophilic agents allowed us to introduce the properly substituted alkyl substituents at C-4 of the 4H-pyrazolo[1,5-a]indoles. The 2,3-dichloro-5,6- dicyano-p-benzoquinone (DDQ) oxidation of these products gave the 3-oxo-2- phenyl-3H-pyrazolo[1,5-a]indole derivatives. Selective keto-enol tautomerizations of these 1,5-diketo-monoene system were observed.

Preparation and reactions of 3H-pyrazolo[1,5-a]indole derivatives

3H-Pyrazolo[1,5-a]indole derivatives were prepared for the first time starting from 3-oxo-2-phenyl-3H-pyrazolo[1,5-a]indole, which was obtained by the 2,3-dichloro-4,5-dicyano-p-benzoquinone (DDQ) oxidation of 3-hydroxy-2- phenyl-3a,4-dihydro-3H-pyrazolo[